Nucleofill 20
Nucleofill 20 is a professional polynucleotide formulation from Promoitalia designed for facial skin rejuvenation and biostimulation. Also identified as Nucleofill Medium in current product references, it is supplied as a 1.5ml syringe and contains polynucleotide gel at 20mg/ml.
Nucleofill 20 Overview
Nucleofill 20 is a polynucleotide-based aesthetic skin booster manufactured by Promoitalia. Current product documentation and professional suppliers also identify the product as Nucleofill Medium, with the “20” referring to its 20mg/ml polynucleotide concentration. The product is supplied in a 1.5ml syringe. :contentReference[oaicite:0]{index=0}
The formulation is based on polynucleotide gel and is positioned for professional skin regeneration, hydration, elasticity and overall facial skin-quality improvement. Technical product information identifies an approximate molecular weight of 2,500 kDa, with a pH range of 6.8–7.2 and viscosity of approximately 28–43 Pa·s. :contentReference[oaicite:1]{index=1}
Nucleofill 20 occupies a distinct position within the Nucleofill portfolio. It differs from Nucleofill Strong, which has a higher polynucleotide concentration, and from the Soft Plus Eyes and Hair formulations, which have different product positioning and formulation characteristics.
Why Choose Nucleofill 20?
The main advantage of Nucleofill 20 for professional clinics is its clearly defined position as a medium-strength polynucleotide formulation for facial skin-quality applications. Its 20mg/ml concentration and 1.5ml presentation make it straightforward to distinguish from the other products in the Nucleofill family.
Product information describes Nucleofill 20 as supporting hydration, regeneration and protection against oxidative stress, while also positioning the formulation around skin elasticity and a lifting effect. These descriptions represent manufacturer or supplier product positioning rather than a guarantee of individual clinical outcomes. :contentReference[oaicite:2]{index=2}
The formulation’s approximately 2,500 kDa molecular weight also distinguishes it from the lower-molecular-weight hair-focused references within the Nucleofill range.
Key Features of Nucleofill 20
20mg/ml Polynucleotides
Nucleofill 20 is identified by its 20mg/ml polynucleotide concentration, giving the product its “20” designation.
1.5ml Syringe
The product is supplied as one 1.5ml syringe according to current professional product listings. :contentReference[oaicite:3]{index=3}
~2,500 kDa
Technical product information identifies an approximate molecular weight of 2,500 kDa.
Hydration Focus
The formulation is positioned around skin hydration and improved overall skin quality.
Skin Regeneration
Nucleofill product information positions the formulation around skin regeneration and biostimulation.
Professional Formulation
Nucleofill 20 is marketed through professional aesthetic and healthcare supply channels.
Nucleofill 20 Formulation
The core active component of Nucleofill 20 is polynucleotide gel. Current product information identifies a concentration of 20mg/ml and a 1.5ml syringe presentation. The stated ingredients in current product documentation include water, sodium DNA and sodium chloride. :contentReference[oaicite:4]{index=4}
Technical specifications identify an approximate molecular weight of 2,500 kDa, pH between 6.8 and 7.2, and viscosity of approximately 28–43 Pa·s. :contentReference[oaicite:5]{index=5}
This formulation profile places Nucleofill 20 within the facial Nucleofill products and differentiates it from the Hair and Soft Plus Eyes references.
Professional Applications
Skin Rejuvenation
Positioned for professional facial skin-rejuvenation and biostimulation treatments.
Hydration
Product information describes a hydrating effect associated with the polynucleotide gel formulation.
Skin Elasticity
Nucleofill 20 is positioned for skin-quality concerns involving elasticity and visible signs of ageing.
Biostimulation
The formulation is marketed as a polynucleotide biostimulator rather than a conventional volumising dermal filler.
Nucleofill 20 vs Other Nucleofill Formulations
The Nucleofill range contains several formulations with different concentrations, molecular weights, volumes and target areas. Nucleofill 20 is currently associated with the former “20” designation and the current “Medium” name. :contentReference[oaicite:6]{index=6}
| Characteristic | Nucleofill 20 | Nucleofill Strong | Nucleofill Soft+ Eyes |
|---|---|---|---|
| Current Name | Nucleofill Medium / 20 | Nucleofill Strong | Nucleofill Soft Plus / Eyes |
| Concentration | 20mg/ml / 2% | 2.5% | 0.75% in current Soft Plus documentation |
| Approx. Molecular Weight | 2,500 kDa | 2,500 kDa | 50–100 kDa |
| Volume | 1.5ml | 1.5ml | 2ml |
| Primary Positioning | Facial skin rejuvenation | More intensive facial biostimulation | Periocular / eye area |
Comparative specifications are based on current professional product documentation and supplier references. Exact packaging and market-specific product naming should be checked against the supplied product documentation.
Nucleofill 20 Specifications
| Brand | Nucleofill |
| Product | Nucleofill 20 |
| Current Manufacturer Name | Nucleofill Medium |
| Manufacturer | Promoitalia Group S.p.A. |
| Product Type | Polynucleotide gel / skin biostimulator |
| Volume | 1.5ml |
| Polynucleotide Concentration | 20mg/ml |
| Equivalent Percentage | 2% |
| Molecular Weight | Approximately 2,500 kDa |
| pH | 6.8–7.2 |
| Viscosity | 28–43 Pa·s |
| Ingredients Listed | Water, Sodium DNA, Sodium Chloride |
| Presentation | 1 × 1.5ml syringe |
| Needles | 2 × 30G × 13mm listed by current product documentation |
| Primary Positioning | Facial skin rejuvenation and biostimulation |
Professional Nucleofill 20 Stock for Clinics
Nucleofill 20 is a useful professional stock option for clinics offering polynucleotide-based facial skin-rejuvenation treatments. Its 1.5ml format and 20mg/ml concentration make it easy to distinguish from the 2ml Hair and Soft Plus Eyes references.
Current supplier catalogues show an important naming transition: Nucleofill Medium 1.5ml is now listed as the product previously known as Nucleofill 20. This means older invoices, product pages and treatment references may use “Nucleofill 20”, while newer catalogues use “Nucleofill Medium”. :contentReference[oaicite:7]{index=7}
Clinics purchasing this product should therefore verify the exact product name, volume, batch information and supplied documentation, especially when comparing the older 20 designation with current Medium-labelled packaging.
Shop Professional Nucleofill 20
Explore Nucleofill 20 and other professional polynucleotide skin boosters available from Pro Aesthetic Supply Europe.
Nucleofill 20 Product Information
Current professional product documentation identifies Nucleofill 20 as a 1.5ml polynucleotide gel at 20mg/ml, with approximately 2,500 kDa molecular weight and viscosity of 28–43 Pa·s. The product is now commonly referred to as Nucleofill Medium. :contentReference[oaicite:8]{index=8}
For current product information, visit:
Nucleofill 20 1 × 1.5ml
.
Another professional supplier reference is available through:
NUCLEOFILL® 20
.
Frequently Asked Questions
What is Nucleofill 20?
Nucleofill 20 is a professional polynucleotide skin booster from Promoitalia. Current product references identify it as Nucleofill Medium and specify a 1.5ml syringe containing polynucleotide gel at 20mg/ml.
Is Nucleofill 20 the same as Nucleofill Medium?
Yes. Current professional catalogues identify Nucleofill Medium 1.5ml as the product previously known as Nucleofill 20. :contentReference[oaicite:9]{index=9}
How much polynucleotide does Nucleofill 20 contain?
The current product specification is 20mg/ml of polynucleotide gel in a 1.5ml syringe, equivalent to a 2% formulation.
What is the molecular weight of Nucleofill 20?
Current product documentation identifies an approximate molecular weight of 2,500 kDa.
How much product is supplied?
Nucleofill 20 is supplied as one 1.5ml syringe. Current product listings also identify two needles with the product, although exact needle specifications should be checked against the supplied packaging.
What is Nucleofill 20 used for?
It is positioned for professional facial skin rejuvenation, hydration, biostimulation, elasticity improvement and skin-quality applications. It is not presented as a conventional volumising hyaluronic-acid dermal filler.
Who should use Nucleofill 20?
Nucleofill 20 is marketed through professional aesthetic and healthcare channels. Practitioners should use it only within their qualifications, training, applicable local requirements and the manufacturer’s current instructions for use.
Order Nucleofill 20
Add Nucleofill 20 to your professional polynucleotide portfolio for facial skin-rejuvenation and biostimulation applications.
Current sources consistently identify Nucleofill 20 as the former name for Nucleofill Medium, supplied as 1 × 1.5ml with a 20mg/ml polynucleotide formulation and approximately 2,500 kDa molecular weight. Some supplier pages differ on the exact supplied needle gauge/length, so the current packaging and IFU should remain the final reference for included accessories.









