Buy Profhilo Online | IBSA NAHYCO Bio-Remodelling HA for UK & EU Clinics
Profhilo is a bio-remodelling injectable hyaluronic acid treatment manufactured in Italy by IBSA Farmaceutici, launched in 2015 and now one of the most widely used skin boosters in Europe. At ProAestheticSupply.eu, you can buy Profhilo with fast delivery across both the UK and EU, verified authenticity, and B2B pricing for licensed clinics.
Unlike a traditional dermal filler, which stays in a defined area to add volume, Profhilo is designed to spread across the tissue — hydrating the skin and stimulating collagen, elastin, and adipocyte stem cell production to improve overall skin quality from within. It’s the first stabilised HA product manufactured without chemical cross-linking agents (BDDE), using IBSA’s patented NAHYCO® technology to bind 32mg of high molecular weight HA with 32mg of low molecular weight HA (64mg total per 2ml syringe) into a Hybrid Cooperative Complex. It’s indicated for areas affected by skin laxity — particularly the malar and sub-malar cheek and jowl areas — and delivered using the BAP (Bio Aesthetic Points) technique, typically just 5 injection points per treatment.
Profhilo is complementary to other aesthetic treatments — combine it with dermal fillers such as our Restylane range, or browse the wider skin boosters category. Products supplied to UK clinics meet UK MHRA-recognised standards, while EU orders carry CE marking under EU MDR. Profhilo is intended strictly for use by licensed healthcare and aesthetic professionals.
Shop Profhilo below — IBSA’s 64mg NAHYCO® hybrid HA bio-remodelling injectable for skin laxity, hydration, and firmness. Shipped to clinics across the UK and EU. Browse our full skin boosters range for more options.
Body Fillers
Buy Bundles
Buy Bundles
A Complete Buying Guide to Profhilo
Profhilo’s NAHYCO® Hybrid Technology thermally cross-links high and low molecular weight hyaluronic acid without BDDE chemical cross-linking agents, producing a Hybrid Cooperative Complex (HCC) with one of the highest HA concentrations on the market. This structure allows Profhilo to spread widely through tissue rather than staying localised — which is why it’s neither a filler nor a conventional skin booster, but a distinct bio-remodelling category of its own.
Is Profhilo a dermal filler or a skin booster?
Neither, strictly speaking. Dermal fillers stay in a defined area to add volume; skin boosters replace lost hyaluronic acid to restore hydration and elasticity. Profhilo does both at once through bio-remodelling — hydrating tissue while actively stimulating collagen and elastin production to remodel sagging skin, making it the only HA injectable specifically noted for improving skin laxity through elastin stimulation.
How is Profhilo administered, and how long do results last?
Profhilo uses the BAP (Bio Aesthetic Points) technique — typically just 5 injection points per side of the face, originally developed for the malar and sub-malar areas but now also used on the neck, hands, and other areas. Visible results are typically reported after the initial two-session protocol, lasting around six months, with a maintenance session every six months recommended to sustain the bio-remodelling effect.
Is there long-term safety data on Profhilo?
Yes — a large-scale post-marketing surveillance study analysing adverse events across over one million patients exposed to Profhilo globally between 2018 and 2023 has been published in peer-reviewed literature, available via PMC.
Can I order Profhilo in the UK as well as the EU?
Yes — ProAestheticSupply.eu ships Profhilo to licensed clinics and practitioners across both the UK and EU. UK orders are fulfilled to MHRA-recognised standards, while EU orders carry full CE marking under EU MDR, giving clinics on either side of the Channel the same authenticity guarantee.
What should I order alongside Profhilo?
Profhilo is complementary to other aesthetic treatments — many practitioners pair it with dermal fillers such as Regenovue for a combined volume-and-remodelling protocol, and TSK needles for precise BAP-technique injection. Browse our complete product catalogue, or check our FAQs for ordering and shipping information.
All Profhilo products on ProAestheticSupply.eu are intended exclusively for use by licensed healthcare professionals and trained aesthetic practitioners, in accordance with applicable UK and EU regulations. Contact our customer support team if you need help incorporating Profhilo into a treatment protocol.